:root{
  --bg:#070b16;--bg2:#0d1324;--panel:#111827;--ink:#ecf0f8;
  --muted:#8896b0;--brand:#5ea1f7;--accent:#34d9c3;--accent2:#a78bfa;
  --border:rgba(255,255,255,.06);--border-h:rgba(255,255,255,.13);
  --card:linear-gradient(168deg,rgba(255,255,255,.035),rgba(255,255,255,.008));
  --glow:rgba(94,161,247,.07);--glow-accent:rgba(52,217,195,.06);
  --serif:'DM Serif Display',Georgia,serif;
  --sans:'DM Sans',system-ui,-apple-system,sans-serif;
  --r:18px;--rs:10px
}
html[data-theme="light"]{
  --bg:#f3f5fb;--bg2:#e9ecf4;--panel:#fff;--ink:#0d1324;
  --muted:#556380;--brand:#2563eb;--accent:#0d9488;--accent2:#7c3aed;
  --border:rgba(13,19,36,.07);--border-h:rgba(13,19,36,.13);
  --card:#fff;--glow:rgba(37,99,235,.04);--glow-accent:rgba(13,148,136,.04)
}
*{box-sizing:border-box;margin:0}
html{scroll-behavior:smooth;scroll-padding-top:80px}
body{background:var(--bg);color:var(--ink);font:400 16px/1.72 var(--sans);-webkit-font-smoothing:antialiased;overflow-x:hidden}
body::before{content:'';position:fixed;inset:0;z-index:-1;pointer-events:none;
  background:radial-gradient(ellipse 1200px 750px at 8% -8%,rgba(94,161,247,.12),transparent),
  radial-gradient(ellipse 1000px 650px at 96% 6%,rgba(52,217,195,.09),transparent),
  radial-gradient(ellipse 700px 500px at 50% 100%,rgba(167,139,250,.07),transparent)}
a{color:var(--brand);text-decoration:none;transition:color .2s}
a:hover{color:var(--accent)}
img{max-width:100%;height:auto}
.container{max-width:1140px;margin:0 auto;padding:0 28px}

/* Header */
header{position:sticky;top:0;z-index:50;backdrop-filter:saturate(140%) blur(16px);-webkit-backdrop-filter:saturate(140%) blur(16px);background:color-mix(in oklab,var(--bg) 78%,transparent);border-bottom:1px solid var(--border)}
header .container{display:flex;align-items:center;justify-content:space-between;height:64px}
.brand{display:flex;align-items:center;gap:12px;text-decoration:none;color:var(--ink)}
.brand:hover{color:var(--ink);text-decoration:none}
.brand-icon{width:40px;height:40px;border-radius:10px;display:grid;place-items:center;background:var(--panel);border:1px solid var(--border);box-shadow:0 2px 12px rgba(0,0,0,.12)}
.brand-text strong{font-size:15px;font-weight:600}
.brand-text .sub{font-size:12px;color:var(--muted);display:block;margin-top:-2px}
.nav-links{display:flex;align-items:center;gap:2px}
.nav-links a{padding:7px 14px;border-radius:8px;font-size:14px;font-weight:500;color:var(--muted);transition:all .2s}
.nav-links a:hover,.nav-links a.active{color:var(--ink);background:var(--glow);text-decoration:none}
.header-r{display:flex;align-items:center;gap:8px}
.theme-btn{width:38px;height:38px;border-radius:10px;border:1px solid var(--border);background:transparent;color:var(--muted);cursor:pointer;display:grid;place-items:center;font-size:16px;transition:all .2s}
.theme-btn:hover{border-color:var(--border-h);color:var(--ink)}
.ham{display:none;width:38px;height:38px;border-radius:10px;border:1px solid var(--border);background:transparent;color:var(--ink);cursor:pointer;place-items:center;font-size:18px}

/* Mobile nav */
.mnav{display:none;position:fixed;inset:0;z-index:100;background:color-mix(in oklab,var(--bg) 96%,transparent);backdrop-filter:blur(24px);flex-direction:column;align-items:center;justify-content:center;gap:6px}
.mnav.open{display:flex}
.mnav a{font-size:20px;padding:14px 36px;border-radius:12px;font-weight:500;color:var(--ink);transition:background .2s}
.mnav a:hover{background:var(--glow);text-decoration:none}
.mnav .xbtn{position:absolute;top:16px;right:20px;width:44px;height:44px;border-radius:12px;border:1px solid var(--border);background:transparent;color:var(--ink);font-size:22px;cursor:pointer;display:grid;place-items:center}

/* Section helpers */
section{padding:72px 0}
.slabel{font-size:11.5px;font-weight:700;letter-spacing:.1em;text-transform:uppercase;color:var(--accent);margin-bottom:8px}
.stitle{font:400 clamp(30px,4vw,46px)/1.12 var(--serif);margin-bottom:14px}
.sdesc{color:var(--muted);max-width:620px;margin-bottom:36px;font-size:16.5px;line-height:1.65}

/* Cards */
.card{background:var(--card);border:1px solid var(--border);border-radius:var(--r);padding:28px;transition:border-color .3s,box-shadow .3s,transform .3s}
.card:hover{border-color:var(--border-h);box-shadow:0 12px 48px var(--glow);transform:translateY(-2px)}
.card h3{font-size:18px;font-weight:600;margin-bottom:8px}
.card p{color:var(--muted)}

/* Buttons */
.cta{display:flex;flex-wrap:wrap;gap:10px}
.btn{display:inline-flex;align-items:center;gap:8px;padding:12px 22px;border-radius:var(--rs);font-size:14px;font-weight:500;border:1px solid var(--border);background:rgba(255,255,255,.04);color:var(--ink);transition:all .25s;text-decoration:none}
.btn:hover{border-color:var(--border-h);background:rgba(255,255,255,.08);color:var(--ink);text-decoration:none;transform:translateY(-1px)}
.btn.primary{background:linear-gradient(135deg,var(--brand),var(--accent));border-color:transparent;color:#fff;box-shadow:0 4px 20px rgba(94,161,247,.25)}
.btn.primary:hover{opacity:.92;color:#fff;box-shadow:0 6px 28px rgba(94,161,247,.35)}
.btn.lg{padding:15px 30px;font-size:16px;border-radius:14px}

/* Tags */
.tag{display:inline-block;padding:3px 10px;border-radius:6px;font-size:11px;font-weight:700;letter-spacing:.04em;text-transform:uppercase;margin-bottom:12px}
.tag-blue{background:rgba(94,161,247,.12);color:var(--brand)}
.tag-teal{background:rgba(52,217,195,.12);color:var(--accent)}
.tag-purple{background:rgba(167,139,250,.12);color:var(--accent2)}

/* Badges */
.badges{display:flex;flex-wrap:wrap;gap:8px;margin-bottom:28px}
.badge{padding:6px 14px;border-radius:999px;font-size:13px;font-weight:500;border:1px solid var(--border);background:rgba(94,161,247,.06);color:var(--brand)}

/* Lists */
.clist{list-style:none;padding:0;display:grid;gap:6px}
.clist li{font-size:14px;padding:9px 12px;border-left:2px solid var(--border);color:var(--muted);transition:border-color .2s}

/* Footer */
footer{padding:32px 0;border-top:1px solid var(--border);font-size:13px;color:var(--muted)}
footer .container{display:flex;justify-content:space-between;align-items:center;flex-wrap:wrap;gap:12px}
.flinks{display:flex;gap:18px}
.flinks a{color:var(--muted);font-size:13px}
.flinks a:hover{color:var(--ink)}

/* Animations */
.fin{opacity:0;transform:translateY(20px);transition:opacity .6s ease,transform .6s ease}
.fin.vis{opacity:1;transform:translateY(0)}
.small{font-size:13px}
.text-muted{color:var(--muted)}

/* ═══ HOME: Hero ═══ */
.hero{position:relative;min-height:calc(100vh - 64px);display:grid;grid-template-columns:1fr 420px;gap:48px;align-items:center;padding:40px 0}
.hero-content{position:relative;z-index:2}
.hero-title{font:400 clamp(36px,5vw,58px)/1.06 var(--serif);margin-bottom:20px;letter-spacing:-.01em}
.hero-sub{color:var(--muted);font-size:18px;line-height:1.65;margin-bottom:24px;max-width:560px}
.hero-photo{position:relative;z-index:2}
.photo-card{overflow:hidden;padding:0;display:flex;flex-direction:column;position:relative}
.photo-card img{width:100%;height:420px;object-fit:cover;object-position:top center;border-radius:var(--r) var(--r) 0 0}
.photo-card .pinfo{padding:20px 24px}
.photo-card .pname{font-size:19px;font-weight:600;margin-bottom:2px}
.photo-card .prole{font-size:13.5px;color:var(--muted);line-height:1.4}
.photo-card .ploc{display:flex;align-items:center;gap:6px;margin-top:10px;font-size:13px;color:var(--accent);font-weight:500}
.hero-glow{position:absolute;top:20%;right:-10%;width:600px;height:600px;border-radius:50%;background:radial-gradient(circle,rgba(94,161,247,.08),transparent 65%);pointer-events:none;z-index:0}

/* ═══ HOME: Clinical Grid ═══ */
.cgrid{display:grid;grid-template-columns:repeat(3,1fr);gap:20px}
.cgrid .card{position:relative;overflow:hidden}
.cgrid .card:nth-child(1) .clist li{border-left-color:rgba(94,161,247,.4)}
.cgrid .card:nth-child(2) .clist li{border-left-color:rgba(52,217,195,.4)}
.cgrid .card:nth-child(3) .clist li{border-left-color:rgba(167,139,250,.4)}

/* ═══ HOME: About ═══ */
.about-grid{display:grid;grid-template-columns:1fr 1fr;gap:24px}
.about-list{list-style:none;padding:0;display:grid;gap:8px}
.about-list li{padding:11px 14px;border-radius:var(--rs);border:1px solid var(--border);font-size:14.5px;background:rgba(255,255,255,.02)}
.about-list li::before{content:'\2192 ';color:var(--accent);font-weight:600}
.aff{display:flex;align-items:center;gap:12px;padding:14px;border-radius:var(--rs);border:1px solid var(--border);font-size:14px;background:rgba(255,255,255,.02)}
.aff-icon{width:40px;height:40px;border-radius:10px;display:grid;place-items:center;font-size:18px;flex-shrink:0}

/* ═══ HOME: Contact ═══ */
.contact-grid{display:grid;grid-template-columns:1fr 1fr;gap:20px}
.contact-card{text-align:center;cursor:pointer}
.contact-card .ci{width:56px;height:56px;border-radius:16px;display:inline-grid;place-items:center;font-size:24px;margin-bottom:14px}
.contact-card:nth-child(1) .ci{background:rgba(94,161,247,.1)}
.contact-card:nth-child(2) .ci{background:rgba(52,217,195,.1)}
.contact-card .clabel{font-size:13px;color:var(--muted);margin-bottom:4px}
.contact-card .cval{font-weight:600;font-size:15.5px;word-break:break-all}
.caddress{margin-top:20px;padding:20px;border-radius:var(--rs);border:1px solid var(--border);background:rgba(255,255,255,.02);text-align:center}
.caddress .ca-l{font-size:11.5px;font-weight:700;letter-spacing:.07em;text-transform:uppercase;color:var(--accent);margin-bottom:6px}
.caddress .ca-t{font-size:14.5px;color:var(--muted)}

/* ═══ SUBPAGES ═══ */
.page-hero{padding:80px 0 48px;text-align:center}
.page-hero .stitle{margin-left:auto;margin-right:auto}
.page-hero .sdesc{margin-left:auto;margin-right:auto}

/* Research */
.rgrid{display:grid;grid-template-columns:1fr 1fr;gap:20px}
.rlist{list-style:none;padding:0;display:grid;gap:8px}
.rlist li{padding:14px;border-radius:var(--rs);border:1px solid var(--border);font-size:15px;background:rgba(255,255,255,.02);transition:border-color .2s}
.rlist li:hover{border-color:var(--border-h)}

/* Publications */
.pub-item{padding:20px 24px;border-radius:var(--rs);border:1px solid var(--border);background:rgba(255,255,255,.02);display:grid;gap:5px;transition:border-color .25s,transform .25s}
.pub-item:hover{border-color:var(--border-h);transform:translateY(-1px)}
.pub-item .ptitle{font-weight:600;font-size:15.5px;line-height:1.4}
.pub-item .pvenue{font-size:13px;color:var(--muted)}
.pub-item .pdoi{font-size:12.5px}
.pub-item .pdoi a{color:var(--accent)}

/* Video */
.vgrid{display:grid;grid-template-columns:repeat(2,1fr);gap:18px}
.vcard{display:grid;grid-template-columns:170px 1fr;gap:16px;align-items:center;padding:16px;border-radius:var(--rs);border:1px solid var(--border);background:rgba(255,255,255,.02);transition:border-color .25s,transform .25s;color:var(--ink);text-decoration:none}
.vcard:hover{border-color:var(--border-h);transform:translateY(-2px);color:var(--ink);text-decoration:none}
.vthumb{width:170px;height:96px;border-radius:8px;object-fit:cover;border:1px solid var(--border);background:var(--bg2)}
.vcard .vt{font-weight:600;font-size:14.5px;line-height:1.35}
.vcard .vtype{font-size:12px;color:var(--muted);margin-top:4px}

/* Privacy */
.priv-list{list-style:none;padding:0;display:grid;gap:8px;margin-top:14px}
.priv-list li{padding:10px 14px;border-radius:var(--rs);border:1px dashed var(--border);font-size:13.5px;color:var(--muted)}

/* Responsive */
@media(max-width:1000px){
  .hero{grid-template-columns:1fr;min-height:auto;padding:48px 0 32px;text-align:center}
  .hero-sub{margin-left:auto;margin-right:auto}
  .badges{justify-content:center}
  .cta{justify-content:center}
  .hero-photo{max-width:380px;justify-self:center}
  .hero-glow{display:none}
  .cgrid{grid-template-columns:1fr}
  .about-grid{grid-template-columns:1fr}
  .rgrid{grid-template-columns:1fr}
  .contact-grid{grid-template-columns:1fr}
  .nav-links{display:none}
  .ham{display:grid}
}
@media(max-width:800px){
  .vgrid{grid-template-columns:1fr}
  .vcard{grid-template-columns:130px 1fr}
  .vthumb{width:130px;height:73px}
}

/* Disclaimer banner — top of procedure/FAQ pages */
.disclaimer-banner{margin-top:-12px}
.dbanner{display:flex;gap:14px;align-items:flex-start;padding:16px 20px;border-radius:var(--rs);background:rgba(245,158,11,.06);border:1px solid rgba(245,158,11,.18);font-size:14.5px;line-height:1.6;color:var(--ink)}
.dbanner strong{color:var(--ink);font-weight:600}
.dbanner a{color:var(--brand);font-weight:500;white-space:nowrap}
.dbanner .dicon{font-size:20px;line-height:1.2;color:#f59e0b;flex-shrink:0;margin-top:1px}
@media(max-width:600px){
  .dbanner{flex-direction:column;gap:8px;font-size:13.5px;padding:14px 16px}
  .dbanner a{white-space:normal}
}

/* FAQ page — clear visual hierarchy: distinct question, separator, breathable answer */
.faq-chips{display:flex;flex-wrap:wrap;gap:10px;margin-top:20px}
.chip{padding:8px 16px;border-radius:999px;font-size:13px;font-weight:500;color:var(--muted);background:var(--glow);border:1px solid var(--border);transition:all .2s}
.chip:hover{color:var(--ink);border-color:var(--border-h);background:var(--glow-accent);text-decoration:none}

.faq-toc{padding-left:0;list-style:none;display:grid;grid-template-columns:1fr 1fr;gap:14px 32px;margin:20px 0 0;font-size:15px;counter-reset:tocnum}
.faq-toc li{margin:0;padding:0;counter-increment:tocnum;line-height:1.5}
.faq-toc li::before{content:counter(tocnum) ".";color:var(--brand);font-weight:600;margin-right:8px}
.faq-toc a{color:var(--muted)}
.faq-toc a:hover{color:var(--brand)}

/* Card list */
.faq-list{display:grid;gap:28px;margin-top:36px}

/* Individual FAQ card */
.faq-item{
  border:1px solid var(--border);
  border-radius:var(--r);
  background:var(--card);
  overflow:hidden;
  transition:border-color .25s,box-shadow .25s,transform .15s;
}
.faq-item:hover{border-color:var(--border-h);transform:translateY(-1px)}
.faq-item[open]{
  border-color:rgba(94,161,247,.35);
  box-shadow:0 6px 32px rgba(94,161,247,.08);
}

/* Question (summary) — distinct colored background that intensifies when open */
.faq-item summary{
  padding:24px 28px;
  font-size:17px;
  font-weight:600;
  color:var(--ink);
  cursor:pointer;
  list-style:none;
  display:flex;
  align-items:flex-start;
  gap:14px;
  line-height:1.55;
  background:linear-gradient(180deg,rgba(94,161,247,.05),rgba(94,161,247,.02));
  border-left:4px solid transparent;
  transition:background .2s,color .2s,border-color .2s;
}
.faq-item summary:hover{
  background:linear-gradient(180deg,rgba(94,161,247,.09),rgba(94,161,247,.04));
  border-left-color:rgba(94,161,247,.4);
  color:var(--brand);
}
.faq-item[open] summary{
  background:linear-gradient(180deg,rgba(94,161,247,.13),rgba(94,161,247,.06));
  border-left-color:var(--brand);
  color:var(--brand);
}
.faq-item summary::-webkit-details-marker{display:none}
.faq-item summary::after{
  content:'+';
  margin-left:auto;
  font-size:26px;
  font-weight:300;
  color:var(--brand);
  flex-shrink:0;
  line-height:1;
  transition:transform .25s ease;
  width:32px;
  height:32px;
  display:flex;
  align-items:center;
  justify-content:center;
  border-radius:50%;
  background:rgba(94,161,247,.08);
}
.faq-item[open] summary::after{
  content:'−';
  background:rgba(94,161,247,.18);
  transform:rotate(180deg);
}
.faq-num{
  color:var(--brand);
  font-weight:700;
  flex-shrink:0;
  min-width:36px;
  font-size:18px;
}

/* Visible delimiter between question and answer */
.faq-answer{
  padding:28px 32px 32px 78px;
  color:var(--ink);
  font-size:15.5px;
  line-height:1.85;
  background:var(--bg);
  border-top:2px solid rgba(94,161,247,.18);
  position:relative;
}
.faq-answer::before{
  content:'';
  display:block;
  position:absolute;
  top:0;left:0;
  width:4px;height:100%;
  background:rgba(94,161,247,.25);
}

/* Answer typography — much more breathing room */
.faq-answer p{margin:0 0 18px;color:var(--muted)}
.faq-answer p:first-child{margin-top:0}
.faq-answer p:last-child{margin-bottom:0}
.faq-answer ul.rlist{margin:20px 0;display:grid;gap:12px}
.faq-answer ul.rlist li{font-size:14.5px;padding:14px 18px;line-height:1.65;color:var(--muted)}
.faq-answer a{color:var(--brand);font-weight:500;border-bottom:1px solid rgba(94,161,247,.3);padding-bottom:1px}
.faq-answer a:hover{color:var(--accent);border-bottom-color:var(--accent)}
.faq-answer strong{color:var(--ink);font-weight:600}

/* Light theme tweaks */
html[data-theme="light"] .faq-item summary{
  background:linear-gradient(180deg,rgba(37,99,235,.04),rgba(37,99,235,.015));
}
html[data-theme="light"] .faq-item[open] summary{
  background:linear-gradient(180deg,rgba(37,99,235,.10),rgba(37,99,235,.04));
}
html[data-theme="light"] .faq-answer{background:rgba(0,0,0,.015)}

@media(max-width:760px){
  .faq-toc{grid-template-columns:1fr;gap:10px 0}
  .faq-list{gap:20px}
  .faq-item summary{padding:20px 22px;font-size:16px;gap:12px}
  .faq-item summary::after{width:28px;height:28px;font-size:22px}
  .faq-answer{padding:24px 22px 24px 22px}
  .faq-num{min-width:30px;font-size:16px}
}